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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WIPF2 All Species: 11.52
Human Site: S71 Identified Species: 25.33
UniProt: Q8TF74 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TF74 NP_573571.1 440 46289 S71 L E K P K G S S G G Y G S G G
Chimpanzee Pan troglodytes XP_511807 182 19950
Rhesus Macaque Macaca mulatta XP_001088658 104 10714
Dog Lupus familis XP_850217 440 46420 S71 L E K P K G S S G G Y G S G A
Cat Felis silvestris
Mouse Mus musculus Q6PEV3 440 46279 S71 I E K P R G S S G G Y G P G A
Rat Rattus norvegicus Q6IN36 487 49732 G66 L D K P K G A G G G Y G G G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517787 163 16570
Chicken Gallus gallus XP_001235113 473 48338 S71 L E K P K G G S G E R G A A G
Frog Xenopus laevis NP_001079978 426 44520 A71 L E T P K G G A G G P G F G A
Zebra Danio Brachydanio rerio NP_001002165 441 45246 G71 I E K P K G G G G G V S S S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P37370 817 82575 A65 G G G V V S S A S G S S G T V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.1 23.6 97.2 N.A. 93.8 39.8 N.A. 24.3 59.2 69.3 69.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 41.3 23.6 98.1 N.A. 96.8 49.2 N.A. 27.9 64.9 77.2 76.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 0 93.3 N.A. 73.3 66.6 N.A. 0 66.6 60 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 0 93.3 N.A. 86.6 80 N.A. 0 73.3 66.6 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 31.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 19 0 0 0 0 10 10 28 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 55 0 0 0 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 10 10 10 0 0 64 28 19 64 64 0 55 19 46 28 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 55 0 55 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 46 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 64 0 0 0 0 0 0 10 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 0 0 0 0 10 37 37 10 0 10 19 28 10 10 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % T
% Val: 0 0 0 10 10 0 0 0 0 0 10 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 37 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _